Workshop on use of intravenous immunoglobulin in hand, foot and mouth disease in Southeast Asia.

ABSTRACT: The South East Asia Infectious Disease Clinical Research Network convened subject matter experts at a workshop to make consensus recommendations for study design of a clinical trial for use of intravenous immunoglobulin (IVIg) in severe hand, foot and mouth disease (HFMD). HFMD is a highly contagious emerging infection among children in the region, a small proportion of whom develop neurologic and cardiopulmonary complications with high case-fatality rates. The use of IVIg for treatment of severe disease is widespread and a part of local, national, and international guidelines, but no clinical evidence warrants the use of this drug, which is expensive and has potentially serious side effects. During a 2-day workshop in March 2014, a group of HFMD experts reviewed the current evidence relat

SUBMITTER: Chea S 

PROVIDER: S-EPMC4285270 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature