Prenatal exposure to traffic pollution: associations with reduced fetal growth and rapid infant weight gain.

ABSTRACT:

Background

Prenatal air pollution exposure inhibits fetal growth, but implications for postnatal growth are unknown.

Methods

We assessed weights and lengths of US infants in the Project Viva cohort at birth and 6 months. We estimated 3rd-trimester residential air pollution exposures using spatiotemporal models. We estimated neighborhood traffic density and roadway proximity at birth address using geographic information systems. We performed linear and logistic regression adjusted for sociodemographic variables, fetal growth, and gestational age at birth.

Results

Mean birth weight-for-gestational age z-score (fetal growth) was 0.17 (standard deviation [SD] = 0.97; n = 2,114), 0- to 6-month weight-for-length gain was 0.23 z-units (SD = 1.11; n = 689), and 17% had weight

SUBMITTER: Fleisch AF 

PROVIDER: S-EPMC4285344 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature