Dramatic decline in substance use by HIV-infected pregnant women in the United States from 1990 to 2012.

ABSTRACT:

Objective

We aimed to describe temporal changes in substance use among HIV-infected pregnant women in the United States from 1990 to 2012.

Design

Data came from two prospective cohort studies (Women and Infants Transmission Study and Surveillance Monitoring for Antiretroviral Therapy Toxicities Study).

Methods

Women were classified as using a substance during pregnancy if they self-reported use or had a positive biological sample. To account for correlation between repeated pregnancies by the same woman, generalized estimating equation models were used to test for temporal trends and evaluate predictors of substance use.

Results

Over the 23-year period, substance use among the 5451 HIV-infected pregnant women sharply declined; 82% of women reported substance us

SUBMITTER: Rough K 

PROVIDER: S-EPMC4285630 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature