Preconception maternal and paternal exposure to persistent organic pollutants and birth size: the LIFE study.

ABSTRACT:

Background

Persistent organic pollutants (POPs) are developmental toxicants, but the impact of both maternal and paternal exposures on offspring birth size is largely unexplored.

Objective

We examined associations between maternal and paternal serum concentrations of 63 POPs, comprising five major classes of pollutants, with birth size measures.

Methods

Parental serum concentrations of 9 organochlorine pesticides, 1 polybrominated biphenyl (PBB), 7 perfluoroalkyl chemicals (PFCs), 10 polybrominated diphenyl ethers (PBDEs), and 36 polychlorinated biphenyls (PCBs) were measured before conception for 234 couples. Differences in birth weight, length, head circumference, and ponderal index were estimated using multiple linear regression per 1-SD increase in natural log-tra

SUBMITTER: Robledo CA 

PROVIDER: S-EPMC4286275 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature