The safe passage study: design, methods, recruitment, and follow-up approach.

ABSTRACT:

Background

The Safe Passage Study is a large, prospective, multidisciplinary study designed to (1) investigate the association between prenatal alcohol exposure, sudden infant death syndrome (SIDS), and stillbirth, and (2) determine the biological basis of the spectrum of phenotypic outcomes from exposure, as modified by environmental and genetic factors that increase the risk of stillbirth, SIDS, and in surviving children, fetal alcohol spectrum disorders.

Methods

The results provided are based on an interim assessment of 6004 women enrolled, out of the 12,000 projected, from the Northern Plains, US, and Cape Town, South Africa, areas known to be of high risk for maternal drinking during pregnancy. Research objectives, study design, and descriptive statistics, including con

SUBMITTER: Dukes KA 

PROVIDER: S-EPMC4286367 | biostudies-literature | 2014 Sep

REPOSITORIES: biostudies-literature