Adipose tissue n-3 fatty acids and metabolic syndrome.

ABSTRACT:

Background

Evidence regarding the relationship of n-3 fatty acids (FA) to type 2 diabetes and metabolic syndrome components (MetS) is inconsistent.

Objective

To examine associations of adipose tissue n-3 FA with MetS.

Design

We studied 1611 participants without prior history of diabetes or heart disease who were participants in a population-based case-control study of diet and heart disease (The Costa Rica Heart Study). We calculated prevalence ratios (PR) and 95% confidence intervals (CI) for MetS by quartile of n-3 FA in adipose tissue derived mainly from plants (α-Linolenic acid (ALA)), fish (eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)) or metabolism (docosapentaenoic acid (DPA), as well as the EPA:ALA ratio, a surrogate marker of delta-6 desaturase

SUBMITTER: Cespedes E 

PROVIDER: S-EPMC4286455 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature