Supplemental Cardioplegia Immediately before Graft Implantation may Improve Early Post-Transplantation Outcome.

ABSTRACT:

Background

Preservation of cardiac grafts for transplantation is not standardized and most centers use a single administration of crystalloid solution at the time of harvesting. We investigated possible benefits of an additional dose of cardioplegia dispensed immediately before implantation.

Methods

Consecutive adult cardiac transplantations (2005-2012) were reviewed. Hearts were harvested following a standard protocol (Celsior 2L, 4-8°C). In 2008, 100 ml crystalloid cardioplegic solution was added and administered immediately before implantation. Univariate and logistic regression analyses were used to investigate risk factors for post-operative graft failure and mid-term outcome.

Results

A total of 81 patients, 44 standard ("Cardio(-)") vs. 37 with additional cardio

SUBMITTER: Tevaearai Stahel HT 

PROVIDER: S-EPMC4286961 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature