The genome of Eimeria falciformis--reduction and specialization in a single host apicomplexan parasite.

ABSTRACT:

Background

The phylum Apicomplexa comprises important unicellular human parasites such as Toxoplasma and Plasmodium. Eimeria is the largest and most diverse genus of apicomplexan parasites and some species of the genus are the causative agent of coccidiosis, a disease economically devastating in poultry. We report a complete genome sequence of the mouse parasite Eimeria falciformis. We assembled and annotated the genome sequence to study host-parasite interactions in this understudied genus in a model organism host.

Results

The genome of E. falciformis is 44 Mb in size and contains 5,879 predicted protein coding genes. Comparative analysis of E. falciformis with Toxoplasma gondii shows an emergence and diversification of gene families associated with motility and invasion ma

SUBMITTER: Heitlinger E 

PROVIDER: S-EPMC4287421 | biostudies-literature | 2014 Aug

REPOSITORIES: biostudies-literature