Metabolomics in psoriatic disease: pilot study reveals metabolite differences in psoriasis and psoriatic arthritis.

ABSTRACT:

Importance

While "omics" studies have advanced our understanding of inflammatory skin diseases, metabolomics is mostly an unexplored field in dermatology.

Objective

We sought to elucidate the pathogenesis of psoriatic diseases by determining the differences in metabolomic profiles among psoriasis patients with or without psoriatic arthritis and healthy controls.

Design

We employed a global metabolomics approach to compare circulating metabolites from patients with psoriasis, psoriasis and psoriatic arthritis, and healthy controls.

Setting

Study participants were recruited from the general community and from the Psoriasis Clinic at the University of California Davis in United States.

Participants

We examined metabolomic profiles using blood serum samples

SUBMITTER: Armstrong AW 

PROVIDER: S-EPMC4288418 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature