Genome wide analysis of Arabidopsis thaliana reveals high frequency of AAAGN7CTTT motif.

ABSTRACT: Sequence specific elements in DNA regulate transcription by recruiting transcription factors. The Dof proteins are a large family of transcription factors that share a single highly conserved zinc finger. The core to which Dof proteins bind has a consensus AAAG or ACTTTA sequence. These motifs have been over represented in many promoters. We performed a genome wide analysis of AAAG repeat elements increasing the spacer length from 0 to 25. Similar analyses was done with AAAG-CTTT motifs. We report unusual high frequency of AAAGN7CTTT in Arabidopsis thaliana genome. We also conclude that there is a preference for A/G nucleotides in spacer sequence between two AAAG repeats.

SUBMITTER: Mehrotra R 

PROVIDER: S-EPMC4288566 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature