What do all the (human) micro-RNAs do?

ABSTRACT:

Background

Micro-RNAs (miRNA) are attributed to the systems biological role of a regulatory mechanism of the expression of protein coding genes. Research has identified miRNAs dysregulations in several but distinct pathophysiological processes, which hints at distinct systems-biology functions of miRNAs. The present analysis approached the role of miRNAs from a genomics perspective and assessed the biological roles of 2954 genes and 788 human miRNAs, which can be considered to interact, based on empirical evidence and computational predictions of miRNA versus gene interactions.

Results

From a genomics perspective, the biological processes in which the genes that are influenced by miRNAs are involved comprise of six major topics comprising biological regulation, cellular meta

SUBMITTER: Ultsch A 

PROVIDER: S-EPMC4289375 | biostudies-literature | 2014 Nov

REPOSITORIES: biostudies-literature