Ability of ambulatory ECG-based T-wave alternans to modify risk assessment of cardiac events: a systematic review.

ABSTRACT:

Background

Exercise-based spectral T-wave alternans (TWA) has been proposed as a noninvasive tool-identifying patients at risk of sudden cardiac death (SCD) and cardiac mortality. Prior studies have indicated that ambulatory electrocardiogram (AECG)-based TWA is an important alternative platform to exercise for risk stratification of cardiac events. This study sought to review data regarding 24-hour AECG-based TWA and to discuss its potential role in risk stratification of fatal cardiac events across a series of patient risk profiles.

Methods

Prospective clinical studies of the predictive value of AECG-based TWA obtained with daily activity published between January 1990 and November 2014 were retrieved. Major endpoints included composite endpoint of SCD, cardiac mortality,

SUBMITTER: Quan XQ 

PROVIDER: S-EPMC4289555 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature