FunRNA: a fungi-centered genomics platform for genes encoding key components of RNAi.

ABSTRACT:

Background

RNA interference (RNAi) is involved in genome defense as well as diverse cellular, developmental, and physiological processes. Key components of RNAi are Argonaute, Dicer, and RNA-dependent RNA polymerase (RdRP), which have been functionally characterized mainly in model organisms. The key components are believed to exist throughout eukaryotes; however, there is no systematic platform for archiving and dissecting these important gene families. In addition, few fungi have been studied to date, limiting our understanding of RNAi in fungi. Here we present funRNA http://funrna.riceblast.snu.ac.kr/, a fungal kingdom-wide comparative genomics platform for putative genes encoding Argonaute, Dicer, and RdRP.

Description

To identify and archive genes encoding the abovement

SUBMITTER: Choi J 

PROVIDER: S-EPMC4290597 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature