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Chromosome-mediated multidrug resistance in Salmonella enterica serovar Typhi.

ABSTRACT: A salmonella genomic island, designated SGI11, was found in 18 of 26 multidrug-resistant Salmonella enterica serovar Typhi isolates from Bangladesh. SGI11 was an IS1 composite transposon and carried 7 resistance genes that conferred resistance to 5 first-line antimicrobials. Eleven of the 18 SGI11-carrying S. Typhi isolates had developed resistance to high levels of ciprofloxacin.

SUBMITTER: Chiou CS 

PROVIDER: S-EPMC4291426 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature

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Chromosome-mediated multidrug resistance in Salmonella enterica serovar Typhi.

Chiou Chien-Shun CS   Alam Munirul M   Kuo Jung-Che JC   Liu Yen-Yi YY   Wang Pei-Jen PJ  

Antimicrobial agents and chemotherapy 20141103 1

A salmonella genomic island, designated SGI11, was found in 18 of 26 multidrug-resistant Salmonella enterica serovar Typhi isolates from Bangladesh. SGI11 was an IS1 composite transposon and carried 7 resistance genes that conferred resistance to 5 first-line antimicrobials. Eleven of the 18 SGI11-carrying S. Typhi isolates had developed resistance to high levels of ciprofloxacin. ...[more]

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