Ontology highlight
ABSTRACT:
SUBMITTER: Lorenzi LE
PROVIDER: S-EPMC4291484 | biostudies-literature | 2015 Jan
REPOSITORIES: biostudies-literature
Lorenzi Luca E LE Bah Amadou A Wischnewski Harry H Shchepachev Vadim V Soneson Charlotte C Santagostino Marco M Azzalin Claus M CM
The EMBO journal 20141114 1
The telomeric transcriptome comprises multiple long non-coding RNAs generated by transcription of linear chromosome ends. In a screening performed in Schizosaccharomyces pombe, we identified factors modulating the cellular levels of the telomeric transcriptome. Among these factors, Cay1 is the fission yeast member of the conserved family of Cactins, uncharacterized proteins crucial for cell growth and survival. In cay1∆ mutants, the cellular levels of the telomeric factor Rap1 are drastically di ...[more]