Noninvasive localization of maximal frequency sites of atrial fibrillation by body surface potential mapping.

ABSTRACT:

Background

Ablation of high-frequency sources in patients with atrial fibrillation (AF) is an effective therapy to restore sinus rhythm. However, this strategy may be ineffective in patients without a significant dominant frequency (DF) gradient. The aim of this study was to investigate whether sites with high-frequency activity in human AF can be identified noninvasively, which should help intervention planning and therapy.

Methods and results

In 14 patients with a history of AF, 67-lead body surface recordings were simultaneously registered with 15 endocardial electrograms from both atria including the highest DF site, which was predetermined by atrial-wide real-time frequency electroanatomical mapping. Power spectra of surface leads and the body surface location of the hi

SUBMITTER: Guillem MS 

PROVIDER: S-EPMC4292880 | biostudies-literature | 2013 Apr

REPOSITORIES: biostudies-literature