Diagnostic ability of retinal nerve fiber layer imaging by swept-source optical coherence tomography in glaucoma.

ABSTRACT:

Purpose

To evaluate the diagnostic accuracies of swept-source optical coherence tomography (OCT) wide-angle and peripapillary retinal nerve fiber layer (RNFL) thickness measurements for glaucoma detection.

Design

Cross-sectional case-control study.

Methods

In this study we enrolled 144 glaucomatous eyes of 106 subjects and 66 eyes of 42 healthy subjects from the Diagnostic Innovations in Glaucoma Study. Glaucoma was defined by the presence of repeatable abnormal standard automated perimetry results and/or progressive glaucomatous optic disc change on masked grading of stereophotographs. Wide-angle and peripapillary RNFL thicknesses were assessed using swept-source OCT. Peripapillary RNFL thickness was also evaluated using spectral-domain OCT. Areas under the receiver

SUBMITTER: Yang Z 

PROVIDER: S-EPMC4293127 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature