Liver injury from herbals and dietary supplements in the U.S. Drug-Induced Liver Injury Network.

ABSTRACT:

Unlabelled

The Drug-Induced Liver Injury Network (DILIN) studies hepatotoxicity caused by conventional medications as well as herbals and dietary supplements (HDS). To characterize hepatotoxicity and its outcomes from HDS versus medications, patients with hepatotoxicity attributed to medications or HDS were enrolled prospectively between 2004 and 2013. The study took place among eight U.S. referral centers that are part of the DILIN. Consecutive patients with liver injury referred to a DILIN center were eligible. The final sample comprised 130 (15.5%) of all subjects enrolled (839) who were judged to have experienced liver injury caused by HDS. Hepatotoxicity caused by HDS was evaluated by expert opinion. Demographic and clinical characteristics and outcome assessments, including d

SUBMITTER: Navarro VJ 

PROVIDER: S-EPMC4293199 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature