Multimodal protocol reduces postoperative nausea and vomiting in patients undergoing Le Fort I osteotomy.

ABSTRACT:

Purpose

To assess the impact of a multimodal antiemetic protocol on postoperative nausea and vomiting (PONV) after Le Fort I osteotomy.

Materials and methods

Consecutive patients undergoing Le Fort I osteotomy with or without additional procedures at a single academic institution were recruited as the intervention cohort for an institutional review board-approved prospective clinical trial with a retrospective comparison group. The intervention cohort was managed with a multimodal antiemetic protocol, including total intravenous anesthesia; prophylactic ondansetron, steroids, scopolamine, and droperidol; gastric decompression at surgery end; opioid-sparing analgesia; avoidance of morphine and codeine; prokinetic erythromycin; and fluids at a minimum of 25 mL/kg. The comparis

SUBMITTER: Brookes CD 

PROVIDER: S-EPMC4293274 | biostudies-literature | 2015 Feb

REPOSITORIES: biostudies-literature