Combined use of Mycobacterium tuberculosis-specific CD4 and CD8 T-cell responses is a powerful diagnostic tool of active tuberculosis.

ABSTRACT: Immune-based assays are promising tools to help to formulate diagnosis of active tuberculosis. A multiparameter flow cytometry assay assessing T-cell responses specific to Mycobacterium tuberculosis and the combination of both CD4 and CD8 T-cell responses accurately discriminated between active tuberculosis and latent infection.

SUBMITTER: Rozot V 

PROVIDER: S-EPMC4293395 | biostudies-literature | 2015 Feb

REPOSITORIES: biostudies-literature