Follicular fluid lipid fingerprinting from women with PCOS and hyper response during IVF treatment.

ABSTRACT:

Purpose

Polycystic ovary syndrome (PCOS) is an endocrine-metabolic disorder that leads to lower natural reproductive potential and presents a challenge for assisted reproductive medicine because patients may exhibit immature oocyte retrieval and a higher risk of ovarian hyper stimulation syndrome during in vitro fertilization (IVF) treatment. This study aimed to identify potential lipid biomarkers for women with PCOS and a hyper response to controlled ovarian stimulation.

Methods

Follicular fluid samples were collected from patients who underwent IVF, including normal responder women who became pregnant (control group, n = 11), women with PCOS and a hyper response to gonadotropins (PCOS group, n = 7) and women with only hyper response to gonadotropins (HR group, n = 7). A li

SUBMITTER: Cordeiro FB 

PROVIDER: S-EPMC4294864 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature