Rates of emergence of HIV drug resistance in resource-limited settings: a systematic review.

ABSTRACT:

Background

The increasing availability of antiretroviral therapy (ART) has improved survival and quality of life for many infected with HIV, but can also engender drug resistance. This review summarizes the available information on drug resistance in adults in resource-limited settings.

Methods

The online databases PubMed and Google Scholar, pertinent conference abstracts and references from relevant articles were searched for publications available before November 2011. Data collected after ART rollout were reviewed.

Results

A total of 7 studies fulfilled the criteria for the analysis of acquired drug resistance and 22 fulfilled the criteria for the analysis of transmitted drug resistance (TDR). Acquired resistance was detected in 7.2% of patients on ART for 6-11 mon

SUBMITTER: Stadeli KM 

PROVIDER: S-EPMC4295493 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature