Multi-modal magnetic resonance elastography for noninvasive assessment of ovarian tissue rigidity in vivo.

ABSTRACT: For centuries, physicians have relied on touch to palpate tissue and detect abnormalities throughout the body. While this time-tested method has provided a simple diagnostic examination for large, superficial abnormalities, it does not permit quantifiable measurements of stiffness in deeper, small organs. Advances in noninvasive imaging to measure tissue rigidity represent important extensions of manual palpation techniques. Tissue fibrosis occurs with age in many organs; in the ovary, it is thought to be a marker of polycystic ovary syndrome and age-related idiopathic infertility, although quantitative assessment of fibrosis in this deep, abdominal tissue has not been possible. We used noninvasive methods to quantify ovarian tissue rigidity and clarify the role of tissue stiffness in repr

SUBMITTER: Wood CD 

PROVIDER: S-EPMC4295766 | biostudies-literature | 2015 Feb

REPOSITORIES: biostudies-literature