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Single-chain semiconducting polymer dots.

ABSTRACT: This work describes the preparation and validation of single-chain semiconducting polymer dots (sPdots), which were generated using a method based on surface immobilization, washing, and cleavage. The sPdots have an ultrasmall size of ∼3.0 nm as determined by atomic force microscopy, a size that is consistent with the anticipated diameter calculated from the molecular weight of the single-chain semiconducting polymer. sPdots should find use in biology and medicine as a new class of fluorescent probes. The FRET assay this work presents is a simple and rapid test to ensure methods developed for preparing sPdot indeed produced single-chain Pdots as designed.

SUBMITTER: Ye F

PROVIDER: S-EPMC4295807 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature

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Single-chain semiconducting polymer dots.

Ye Fangmao F Sun Wei W Zhang Yue Y Wu Changfeng C Zhang Xuanjun X Yu Jiangbo J Rong Yu Y Zhang Miqin M Chiu Daniel T DT

Langmuir : the ACS journal of surfaces and colloids 20141218 1

This work describes the preparation and validation of single-chain semiconducting polymer dots (sPdots), which were generated using a method based on surface immobilization, washing, and cleavage. The sPdots have an ultrasmall size of ∼3.0 nm as determined by atomic force microscopy, a size that is consistent with the anticipated diameter calculated from the molecular weight of the single-chain semiconducting polymer. sPdots should find use in biology and medicine as a new class of fluorescent p ...[more]

PMID: 25521606

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