Toll-like receptor 9 gene polymorphism in chronic and aggressive periodontitis patients.

ABSTRACT:

Aim

Periodontitis is a multifactorial disease, with microbial dental plaque as the primary etiological factor. However, the manifestation and progression of periodontitis is influenced by a wide variety of other determinants and factors such as social and behavioral factors, systemic factors, microbial composition of dental plaque, genetic, and many other emerging risk factors. The aim of this study was to analyze genetic polymorphisms in the toll-like receptor 9 (TLR9) gene at - 1237C/T and its association with chronic and generalized aggressive periodontitis (GAgP) in an Indian population.

Materials and methods

This study was carried out on 90 subjects, which included 30 GAgP and 30 chronic periodontitis patients and 30 healthy controls. Within the limitations of our study

SUBMITTER: Ashok N 

PROVIDER: S-EPMC4296456 | biostudies-literature | 2014 Nov-Dec

REPOSITORIES: biostudies-literature