Identification of ubiquinol binding motifs at the Qo-site of the cytochrome bc1 complex.

ABSTRACT: Enzymes of the bc1 complex family power the biosphere through their central role in respiration and photosynthesis. These enzymes couple the oxidation of quinol molecules by cytochrome c to the transfer of protons across the membrane, to generate a proton-motive force that drives ATP synthesis. Key for the function of the bc1 complex is the initial redox process that involves a bifurcated electron transfer in which the two electrons from a quinol substrate are passed to different electron acceptors in the bc1 complex. The electron transfer is coupled to proton transfer. The overall mechanism of quinol oxidation by the bc1 complex is well enough characterized to allow exploration at the atomistic level, but details are still highly controversial. The controversy stems from the uncertain bin

SUBMITTER: Barragan AM 

PROVIDER: S-EPMC4297238 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature