A preliminary randomized controlled trial of a distress tolerance treatment for opioid dependent persons initiating buprenorphine.

ABSTRACT:

Background

Buprenorphine opioid agonist treatment (OAT) has established efficacy for treating opioid dependency but early relapse rates are high and are often associated with withdrawal-related or emotional distress.

Methods

To determine whether a novel distress tolerance (DT) intervention during buprenorphine initiation decreases opioid relapse, we conducted a preliminary randomized controlled trial with opioid-dependent outpatients. Participants received buprenorphine-naloxone induction and 3-months of maintenance buprenorphine plus seven, 50-min manualized, individual sessions (DT vs. health education (HE) control) over a 28-day period, linked to clinician medication dosing visits, and beginning 2 days prior to buprenorphine induction. Primary outcomes included use of ill

SUBMITTER: Stein MD 

PROVIDER: S-EPMC4297723 | biostudies-literature | 2015 Feb

REPOSITORIES: biostudies-literature