A new type of toxin A-negative, toxin B-positive Clostridium difficile strain lacking a complete tcdA gene.

ABSTRACT: Toxins A and B are the main virulence factors of Clostridium difficile and are the targets for molecular diagnostic tests. Here, we describe a new toxin A-negative, toxin B-positive, binary toxin CDT (Clostridium difficile transferase)-negative (A(-) B(+) CDT(-)) toxinotype (XXXII) characterized by a variant type of pathogenicity locus (PaLoc) without tcdA and with atypical organization of the PaLoc integration site.

SUBMITTER: Janezic S 

PROVIDER: S-EPMC4298534 | biostudies-literature | 2015 Feb

REPOSITORIES: biostudies-literature