Arterial hyperoxia and mortality in critically ill patients: a systematic review and meta-analysis.

ABSTRACT:

Introduction

The safety of arterial hyperoxia is under increasing scrutiny. We performed a systematic review of the literature to determine whether any association exists between arterial hyperoxia and mortality in critically ill patient subsets.

Methods

Medline, Thomson Reuters Web of Science and Scopus databases were searched from inception to June 2014. Observational or interventional studies evaluating the relationship between hyperoxia (defined as a supranormal arterial O2 tension) and mortality in adult intensive care unit (ICU) patients were included. Studies primarily involving patients with exacerbations of chronic pulmonary disease, acute lung injury and perioperative administration were excluded. Adjusted odds ratio (OR) of patients exposed versus those not expose

SUBMITTER: Damiani E 

PROVIDER: S-EPMC4298955 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature