Acute kidney injury after valvular heart surgery and early changes in cardiac function and structure.

ABSTRACT:

Background

Acute kidney injury (AKI) following heart surgery is associated with long-term risk of heart failure. It is not known if AKI following valvular heart surgery is associated with early changes in cardiac function or structure.

Methods

A cohort study was conducted on 201 patients with AKI and 201 patients without AKI after valvular heart surgery, who were matched for age, sex, left ventricular function, and estimated glomerular filtration rate. AKI was defined as an increase in postoperative serum creatinine of ≥26 μmol/l (≥0.3 mg/dl) or a relative increase of ≥50%. The two primary outcomes were changes in post-compared with preoperative left ventricular ejection fraction (LVEF) and left ventricular end-diastolic diameter (LVEDD) assessed by echocardiography.

Resu

SUBMITTER: Olsson DP 

PROVIDER: S-EPMC4299171 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature