RNA-seq analysis of broiler liver transcriptome reveals novel responses to high ambient temperature.

ABSTRACT:

Background

In broilers, high ambient temperature can result in reduced feed consumption, digestive inefficiency, impaired metabolism, and even death. The broiler sector of the U.S. poultry industry incurs approximately $52 million in heat-related losses annually. The objective of this study is to characterize the effects of cyclic high ambient temperature on the transcriptome of a metabolically active organ, the liver. This study provides novel insight into the effects of high ambient temperature on metabolism in broilers, because it is the first reported RNA-seq study to characterize the effect of heat on the transcriptome of a metabolic-related tissue. This information provides a platform for future investigations to further elucidate physiologic responses to high ambient tempera

SUBMITTER: Coble DJ 

PROVIDER: S-EPMC4299486 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature