Evolution and gene capture in ancient endogenous retroviruses - insights from the crocodilian genomes.

ABSTRACT:

Background

Crocodilians are thought to be hosts to a diverse and divergent complement of endogenous retroviruses (ERVs) but a comprehensive investigation is yet to be performed. The recent sequencing of three crocodilian genomes provides an opportunity for a more detailed and accurate representation of the ERV diversity that is present in these species. Here we investigate the diversity, distribution and evolution of ERVs from the genomes of three key crocodilian species, and outline the key processes driving crocodilian ERV proliferation and evolution.

Results

ERVs and ERV related sequences make up less than 2% of crocodilian genomes. We recovered and described 45 ERV groups within the three crocodilian genomes, many of which are species specific. We have also revealed a ne

SUBMITTER: Chong AY 

PROVIDER: S-EPMC4299795 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature