Training-induced improvements in postural control are accompanied by alterations in cerebellar white matter in brain injured patients.

ABSTRACT: We investigated whether balance control in young TBI patients can be promoted by an 8-week balance training program and whether this is associated with neuroplastic alterations in brain structure. The cerebellum and cerebellar peduncles were selected as regions of interest because of their importance in postural control as well as their vulnerability to brain injury. Young patients with moderate to severe TBI and typically developing (TD) subjects participated in balance training using PC-based portable balancers with storage of training data and real-time visual feedback. An additional control group of TD subjects did not attend balance training. Mean diffusivity and fractional anisotropy were determined with diffusion MRI scans and were acquired before, during (4 weeks) and at completion

SUBMITTER: Drijkoningen D 

PROVIDER: S-EPMC4300016 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature