Sporadic visual acuity loss in the Comparison of Age-Related Macular Degeneration Treatments Trials (CATT).

ABSTRACT:

Purpose

To evaluate transient, large visual acuity (VA) decreases, termed sporadic vision loss, during anti-vascular endothelial growth factor treatment for neovascular age-related macular degeneration (AMD).

Design

Cohort within a randomized clinical trial.

Methods

setting: Comparison of Age-Related Macular Degeneration Treatments Trials (CATT). study population: Total of 1185 CATT patients. main outcome measures: Incidence of sporadic vision loss and odds ratio (OR) for association with patient and ocular factors. Sporadic vision loss was a decline of ≥15 letters from the previous visit, followed by a return at the next visit to no more than 5 letters worse than the visit before the VA loss.

Results

There were 143 sporadic vision loss events in 122 of 1185 pa

SUBMITTER: Kim BJ 

PROVIDER: S-EPMC4301065 | biostudies-literature | 2014 Jul

REPOSITORIES: biostudies-literature