Maternal nutrition induces gene expression changes in fetal muscle and adipose tissues in sheep.

ABSTRACT:

Background

Maternal nutrition during different stages of pregnancy can induce significant changes in the structure, physiology, and metabolism of the offspring. These changes could have important implications on food animal production especially if these perturbations impact muscle and adipose tissue development. Here, we evaluated the impact of different maternal isoenergetic diets, alfalfa haylage (HY; fiber), corn (CN; starch), and dried corn distillers grains (DG; fiber plus protein plus fat), on the transcriptome of fetal muscle and adipose tissues in sheep.

Results

Prepartum diets were associated with notable gene expression changes in fetal tissues. In longissimus dorsi muscle, a total of 224 and 823 genes showed differential expression (FDR ≤0.05) in fetuses derived

SUBMITTER: Penagaricano F 

PROVIDER: S-EPMC4301459 | biostudies-literature | 2014 Nov

REPOSITORIES: biostudies-literature