Dietary Yeasts Reduce Inflammation in Central Nerve System via Microflora.

ABSTRACT:

Objectives

The intestinal microflora affects the pathogenesis of several autoimmune diseases by influencing immune system function. Some bacteria, such as lactic acid bacteria, have been reported to have beneficial effects on immune function. However, little is known about the effects of yeasts. Here, we aimed to investigate the effects of various dietary yeasts contained in fermented foods on experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis (MS), and to elucidate the mechanisms underlying these effects.

Methods

The effects of eight yeasts selected from 18 types of yeasts contained in fermented foods were examined using an EAE model. Of these, Candida kefyr was investigated by analyzing the intestinal microflora and its effects on intest

SUBMITTER: Takata K 

PROVIDER: S-EPMC4301675 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature