Improving the pre-screening of eligible patients in order to increase enrollment in cancer clinical trials.

ABSTRACT:

Background

The performance of randomized controlled trials (RCTs) is often hindered by recruitment difficulties. This study aims to explore the pre-screening phase of four prostate cancer RCTs to identify the impact of a systematic pre-selection of eligible patients for RCT recruitment.

Methods

The pre-screening of four RCTs opened at the Comprehensive Cancer Center in Rennes was analyzed retrospectively (French Genitourinary Tumor Group (GETUG) 14, 15, 16, and 17). Data were extracted from electronic multidisciplinary cancer (MDC) reports and manually completed by physicians and medical secretaries. These data were the main source of information for clinicians to discuss treatment alternatives during MDC sessions. The pre-screening decisions made by the clinicians during th

SUBMITTER: Campillo-Gimenez B 

PROVIDER: S-EPMC4301877 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature