A population-based cohort study on adherence to practice guidelines for adjuvant chemotherapy in colorectal cancer.

ABSTRACT:

Background

The value of adjuvant chemotherapy in colorectal cancer is well studied, and guidelines have been established. Little is known about how treatment guidelines are implemented in the everyday clinical setting.

Methods

This national population-based study on nearly 34,000 patients with colorectal cancer evaluates the adherence to present clinical guidelines for adjuvant chemotherapy. Virtually all patients with colorectal cancer in Sweden during the years 2007-2012 and data from the Swedish Colorectal Cancer Registry were included.

Results

In colon cancer stage III, adherence to national guidelines was associated with lower age, presence of multidisciplinary team (MDT) conference, low co-morbidity, and worse N stage. The MDT forum also affected whether or not

SUBMITTER: Lindskog EB 

PROVIDER: S-EPMC4301907 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature