Low-density-lipoprotein particle size predicts a poor outcome in patients with atherothrombotic stroke.

ABSTRACT:

Background and purpose

Low-density lipoprotein (LDL) particle size is considered to be one of the more important cardiovascular risk factors, and small LDL particles are known to have atherogenic potential. The aim of this study was to determine whether LDL particle size is associated with stroke severity and functional outcome in patients with atherothrombotic stroke.

Methods

Between January 2009 and May 2011, 248 patients with first-episode cerebral infarction who were admitted to our hospital within 7 days after symptom onset were prospectively enrolled. LDL particle size was measured using the nondenaturing polyacrylamide gradient gel electrophoresis assay. Stroke severity was assessed by applying the National Institutes of Health Stroke Scale (NIHSS) at admission. Funct

SUBMITTER: Song TJ 

PROVIDER: S-EPMC4302183 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature