Primary squamous cell carcinomas in the thyroid gland: an individual participant data meta-analysis.

ABSTRACT: Primary squamous cell carcinomas arising from the thyroid gland (SCCTh) is extremely rare diseases, which have never been fully studied. Thus, we performed a systematic review and individual participant data meta-analysis of published SCCTh cases, to understand the clinical characteristics and to identify the prognostic factors of primary SCCTh. A literature search was conducted within Medline, EMBASE, Cochrane library databases and KoreaMed using the following Medical Subject Headings (MeSH) keywords: "primary," "squamous," "carcinoma," "cancer," and "thyroid." Eighty-four patients' individual data from 39 articles and five patients' data in our institute were selected for analysis (N = 89). The mean age at diagnosis was 63.0 years (range, 24-90) and female preponderance (M:F = 1:2) was n

SUBMITTER: Cho JK 

PROVIDER: S-EPMC4302690 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature