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Methanothermobacter thermautotrophicus modulates its membrane lipids in response to hydrogen and nutrient availability.


ABSTRACT: Methanothermobacter thermautotrophicus strain ΔH is a model hydrogenotrophic methanogen, for which extensive biochemical information, including the complete genome sequence, is available. Nevertheless, at the cell membrane lipid level, little is known about the responses of this archaeon to environmental stimuli. In this study, the lipid composition of M. thermautotrophicus was characterized to verify how this archaeon modulates its cell membrane components during growth phases and in response to hydrogen depletion and nutrient limitation (potassium and phosphate). As opposed to the higher abundance of phospholipids in the stationary phase of control experiments, cell membranes under nutrient, and energy stress were dominated by glycolipids that likely provided a more effective barrier aga

SUBMITTER: Yoshinaga MY 

PROVIDER: S-EPMC4302986 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature