The influence of HIV and schistosomiasis on renal function: a cross-sectional study among children at a hospital in Tanzania.

ABSTRACT:

Background

Schistosomiasis and HIV are both associated with kidney disease. Prevalence and factors associated with abnormal renal function among HIV-infected children in Africa compared to uninfected controls have not been well described in a schistosomiasis endemic area.

Methodology/principal findings

This cross-sectional study was conducted at the Sekou Toure Regional Hospital HIV clinic in Mwanza, Tanzania. A total of 122 HIV-infected children and 122 HIV-uninfected siblings were consecutively enrolled. Fresh urine was obtained for measurement of albuminuria and Schistosoma circulating cathodic antigen. Blood was collected for measurement of serum creatinine. Estimated glomerular filtration rate (eGFR) was calculated using the modified Schwartz equation. Renal dysfunction

SUBMITTER: Kayange NM 

PROVIDER: S-EPMC4303314 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature