Study of minor physical anomalies in complete nuclear Mexican families. Evidence of neurodevelopmental problems in schizophrenia.

ABSTRACT:

Introduction

Minor physical anomalies (MPA) are dysmorphic features that reflect deviations in early development, are morphological variants that appear during the first trimester of pregnancy and could be used as a marker of disease risk in susceptible people. The literature agrees that the number of MPA is higher in patients with schizophrenia compared with their relatives and healthy subjects. The purpose of this study is to compare the MPA, assessed using the Gourion Scale, in complete nuclear families (families with a member with schizophrenia and control families) by determining the MPA mean, concordance and heritability for the total score on the MPA Gourion Scale for each anomaly.

Method

The sample consisted of 60 families with at least one schizophrenic patient (284

SUBMITTER: Ambrosio-Gallardo F 

PROVIDER: S-EPMC4303412 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature