Surgical treatment of moderate ischemic mitral regurgitation.

ABSTRACT:

Background

Ischemic mitral regurgitation is associated with increased mortality and morbidity. For surgical patients with moderate regurgitation, the benefits of adding mitral-valve repair to coronary-artery bypass grafting (CABG) are uncertain.

Methods

We randomly assigned 301 patients with moderate ischemic mitral regurgitation to CABG alone or CABG plus mitral-valve repair (combined procedure). The primary end point was the left ventricular end-systolic volume index (LVESVI), a measure of left ventricular remodeling, at 1 year. This end point was assessed with the use of a Wilcoxon rank-sum test in which deaths were categorized as the lowest LVESVI rank.

Results

At 1 year, the mean LVESVI among surviving patients was 46.1±22.4 ml per square meter of body-surface ar

SUBMITTER: Smith PK 

PROVIDER: S-EPMC4303577 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature