Diabetic foot syndrome: Immune-inflammatory features as possible cardiovascular markers in diabetes.

ABSTRACT: Diabetic foot ulcerations have been extensively reported as vascular complications of diabetes mellitus associated with a high degree of morbidity and mortality. Diabetic foot syndrome (DFS), as defined by the World Health Organization, is an "ulceration of the foot (distally from the ankle and including the ankle) associated with neuropathy and different grades of ischemia and infection". Pathogenic events able to cause diabetic foot ulcers are multifactorial. Among the commonest causes of this pathogenic pathway it's possible to consider peripheral neuropathy, foot deformity, abnormal foot pressures, abnormal joint mobility, trauma, peripheral artery disease. Several studies reported how diabetic patients show a higher mortality rate compared to patients without diabetes and in particula

SUBMITTER: Tuttolomondo A 

PROVIDER: S-EPMC4303791 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature