A family cluster of three confirmed cases infected with avian influenza A (H7N9) virus in Zhejiang Province of China.

ABSTRACT:

Background

A total of 453 laboratory-confirmed cases infected with avian influenza A (H7N9) virus (including 175 deaths) have been reported till October 2,2014, of which 30.68% (139/453) of the cases were identified from Zhejiang Province. We describe the largest reported cluster of virologically confirmed H7N9 cases, comprised by a fatal Index case and two mild secondary cases.

Methods

A retrospective investigation was conducted in January of 2014. Three confirmed cases, their close contacts, and relevant environments samples were tested by real-time reverse transcriptase-polymerase chain reaction (RT-PCR), viral culture, and sequencing. Serum samples were tested by haemagglutination inhibition (HI) assay.

Results

The Index case, a 49-year-old farmer with type II dia

SUBMITTER: Ding H 

PROVIDER: S-EPMC4304124 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature