Mode of childbirth and long-term outcomes in women with inflammatory bowel diseases.

ABSTRACT:

Introduction

Inflammatory bowel diseases [IBD; Crohn's disease (CD), ulcerative colitis] often affect women in their reproductive years. Few studies have analyzed the impact of mode of childbirth on long-term IBD outcomes.

Methods

We used a multi-institutional IBD cohort to identify all women in the reproductive age-group with a diagnosis of IBD prior to pregnancy. We identified the occurrence of a new diagnosis code for perianal complications, IBD-related hospitalization and surgery, and initiation of medical therapy after either a vaginal delivery or caesarean section (CS). Cox proportional hazards models adjusting for potential confounders were used to estimate independent effect of mode of childbirth on IBD outcomes.

Results

Our cohort included 360 women with IBD

SUBMITTER: Ananthakrishnan AN 

PROVIDER: S-EPMC4304947 | biostudies-literature | 2015 Feb

REPOSITORIES: biostudies-literature