Prognostic role of microRNA-205 in multiple human malignant neoplasms: a meta-analysis of 17 studies.

ABSTRACT:

Objective

MicroRNA-205 (miRNA-205) was revealed as an attractive prognostic tumour biomarker in recent studies. However, the results of different studies have been inconsistent. We conducted a meta-analysis to elucidate the precise predictive value of miRNA-205 in various human malignant neoplasms.

Design

Meta-analysis.

Data sources

Qualified studies were identified up to 5 June 2014 by performing online searches in PubMed, EMBASE and Web of Science, and additional quality evaluations.

Participants

Seventeen eligible studies with 4827 patients were ultimately enrolled in this meta-analysis.

Outcome measures

The heterogeneity between studies was assessed using I(2) statistics. Pooled HRs with 95% CIs for patient survival and disease recurrence were calcul

SUBMITTER: Zhang JY 

PROVIDER: S-EPMC4305071 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature