The development of human amygdala functional connectivity at rest from 4 to 23 years: a cross-sectional study.

ABSTRACT: Functional connections (FC) between the amygdala and cortical and subcortical regions underlie a range of affective and cognitive processes. Despite the central role amygdala networks have in these functions, the normative developmental emergence of FC between the amygdala and the rest of the brain is still largely undefined. This study employed amygdala subregion maps and resting-state functional magnetic resonance imaging to characterize the typical development of human amygdala FC from age 4 to 23years old (n=58). Amygdala FC with subcortical and limbic regions was largely stable across this developmental period. However, three cortical regions exhibited age-dependent changes in FC: amygdala FC with the medial prefrontal cortex (mPFC) increased with age, amygdala FC with a region includ

SUBMITTER: Gabard-Durnam LJ 

PROVIDER: S-EPMC4305511 | biostudies-literature | 2014 Jul

REPOSITORIES: biostudies-literature