Association between 7 years of intensive treatment of type 1 diabetes and long-term mortality.

ABSTRACT:

Importance

Whether mortality in type 1 diabetes mellitus is affected following intensive glycemic therapy has not been established.

Objective

To determine whether mortality differed between the original intensive and conventional treatment groups in the long-term follow-up of the Diabetes Control and Complications Trial (DCCT) cohort.

Design, setting, and participants

After the DCCT (1983-1993) ended, participants were followed up in a multisite (27 US and Canadian academic clinical centers) observational study (Epidemiology of Diabetes Control and Complications [EDIC]) until December 31, 2012. Participants were 1441 healthy volunteers with diabetes mellitus who, at baseline, were 13 to 39 years of age with 1 to 15 years of diabetes duration and no or early microvascu

SUBMITTER: Writing Group for the DCCT/EDIC Research Group 

PROVIDER: S-EPMC4306335 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature